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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9022 | AZD9977 | AZD 9977 | Glucocorticoid Receptor |
AZD9977 is a novel, selective modulator of mineralocorticoid receptor . | |||
T0083 | Eplerenone | Epoxymexrenone,CGP 30083,SC-66110 | Glucocorticoid Receptor |
Eplerenone (CGP 30083) is an aldosterone receptor antagonist and potassium-sparing diuretic used in the therapy of hypertension. Eplerenone therapy has been associated with transient elevations in serum aminotransferase ... | |||
T6542 | Imidapril hydrochloride | Novaloc,Imidapril HCl,Tanapril,TA-6366 | RAAS |
Imidapril hydrochloride (Tanapril) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension. | |||
T2006 | Omecamtiv mecarbil | CK-1827452 | ATPase , Myosin |
Omecamtiv mecarbil (CK-1827452) has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic Heart Failure, and History of Chronic Heart Failure, among othe... | |||
T27596 | Imazodan hydrochloride | CI914 HCl,CI-914 HCl,CI 914 HCl,Imazodan HCl | PDE |
Imazodan hydrochloride (CI-914 HCl) is a potent and selective type III phosphodiesterase inhibitor used in the treatment of chronic congestive heart failure. | |||
T10631 | Bucindolol | BMY 13105,MJ 131051,MJ 13105 | Adrenergic Receptor |
Bucindolol (BMY 13105) is a novel and potent β1-adrenergic receptor blocker that mediates vasodilation and can be used to study chronic heart failure. | |||
T6486 | Enalapril Maleate | MK-421 Maleate,Renitec Maleate,Glioten Maleate,MK-421 (maleate),Vasotec Maleate | RAAS |
Enalapril Maleate (MK-421 Maleate), an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension, chronic heart failure , and diabetic nephropathy. | |||
T33711L | Nolomirole HCl | CHF 1035 HCl,CHF 1035,CHF1035,CHF1035 HCl,CHF-1035 HCl,CHF-1035,Nolomirole Hydrochloride | Dopamine Receptor , Norepinephrine |
Nolomirole HCl (CHF 1035) is a novel selective dopamine agonist with oral activity and inhibitory effects on norepinephrine release, which can be used to study mild chronic heart failure. | |||
T0154 | Nebivolol hydrochloride | R 065824 hydrochloride,Nebivolol HCl,R-65824 | Apoptosis , Adrenergic Receptor |
Nebivolol hydrochloride (R 065824 hydrochloride) is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is us... | |||
T21395 | Finerenone | BAY948862,BAY-948862,BAY94-8862,BAY 94-8862,BAY-94-8862,BAY 948862 | Glucocorticoid Receptor |
Finerenone (BAY-948862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart failure. Finerenone (BAY-948862... | |||
T68138 | Saterinone | Adrenergic Receptor , PDE | |
Saterinone is a potent and selective phosphodiesterase III inhibitor and a potent antagonist of the vascular α-1-adrenoceptor. Saterinone has vasodilatory properties and can be used in the acute treatment of chronic hear... | |||
T13599 | Benzofurodil | CB4091,Benfurodil,Eudilat | Others |
Benzofurodil is cardiotonic used for the chronic treatment of congestive heart failure. | |||
T39063 | Azilsartan mepixetil | ||
Azilsartan mepixetil is a potent angiotensin II receptor antagonist with enhanced efficacy and prolonged duration of action. It exhibits more prominent and sustained effects in lowering blood pressure and heart rate, whi... | |||
T61407 | TRPC3/6-IN-1 | ||
TRPC3/6-IN-1 is a highly potent and selective inhibitor that specifically blocks the activity of the canonical transient receptor channels TRPC3 and TRPC6. It exhibits a significant blocking potency against the human iso... | |||
T78657 | Azilsartan mepixetil potassium | QR-01019K | |
Azilsartan medoxomil potassium (QR-01019K), an angiotensin II receptor antagonist, exhibits a potent and sustained antihypertensive effect, along with a more pronounced and enduring reduction in heart rate, and a high sa... | |||
T21485 | Perindopril | ||
Perindopril (S-9490) is a long-acting ACE inhibitor effective for 24 hours, primarily utilized in the management of high blood pressure, heart failure, or stable coronary artery disease. Available as perindopril arginine... | |||
T62005 | Imidapril | ||
Imidapril (TA-6366 free base) is an orally active inhibitor of angiotensin-converting enzyme (ACE) and MMP-9. Imidapril inhibits the conversion of angiotensin I to angiotensin II, thereby reduces total peripheral resista... | |||
T72213 | Efonidipine hydrochloride | NZ-105 hydrochloride | |
Efonidipine HCl (NZ-105) serves as both a T-type and L-type calcium channel blocker. This compound, distinct from other calcium channel blockers, notably increases N(6), 2'-O-dibutyryladenosine 3',5'-cyclic monophosphate... |