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Search Results for " chronic heart failure "

18

Compounds

Cat No. Product Name Synonyms Targets
T9022 AZD9977 AZD 9977 Glucocorticoid Receptor
AZD9977 is a novel, selective modulator of mineralocorticoid receptor .
T0083 Eplerenone Epoxymexrenone,CGP 30083,SC-66110 Glucocorticoid Receptor
Eplerenone (CGP 30083) is an aldosterone receptor antagonist and potassium-sparing diuretic used in the therapy of hypertension. Eplerenone therapy has been associated with transient elevations in serum aminotransferase ...
T6542 Imidapril hydrochloride Novaloc,Imidapril HCl,Tanapril,TA-6366 RAAS
Imidapril hydrochloride (Tanapril) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.
T2006 Omecamtiv mecarbil CK-1827452 ATPase , Myosin
Omecamtiv mecarbil (CK-1827452) has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic Heart Failure, and History of Chronic Heart Failure, among othe...
T27596 Imazodan hydrochloride CI914 HCl,CI-914 HCl,CI 914 HCl,Imazodan HCl PDE
Imazodan hydrochloride (CI-914 HCl) is a potent and selective type III phosphodiesterase inhibitor used in the treatment of chronic congestive heart failure.
T10631 Bucindolol BMY 13105,MJ 131051,MJ 13105 Adrenergic Receptor
Bucindolol (BMY 13105) is a novel and potent β1-adrenergic receptor blocker that mediates vasodilation and can be used to study chronic heart failure.
T6486 Enalapril Maleate MK-421 Maleate,Renitec Maleate,Glioten Maleate,MK-421 (maleate),Vasotec Maleate RAAS
Enalapril Maleate (MK-421 Maleate), an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension, chronic heart failure , and diabetic nephropathy.
T33711L Nolomirole HCl CHF 1035 HCl,CHF 1035,CHF1035,CHF1035 HCl,CHF-1035 HCl,CHF-1035,Nolomirole Hydrochloride Dopamine Receptor , Norepinephrine
Nolomirole HCl (CHF 1035) is a novel selective dopamine agonist with oral activity and inhibitory effects on norepinephrine release, which can be used to study mild chronic heart failure.
T0154 Nebivolol hydrochloride R 065824 hydrochloride,Nebivolol HCl,R-65824 Apoptosis , Adrenergic Receptor
Nebivolol hydrochloride (R 065824 hydrochloride) is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is us...
T21395 Finerenone BAY948862,BAY-948862,BAY94-8862,BAY 94-8862,BAY-94-8862,BAY 948862 Glucocorticoid Receptor
Finerenone (BAY-948862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart failure. Finerenone (BAY-948862...
T68138 Saterinone Adrenergic Receptor , PDE
Saterinone is a potent and selective phosphodiesterase III inhibitor and a potent antagonist of the vascular α-1-adrenoceptor. Saterinone has vasodilatory properties and can be used in the acute treatment of chronic hear...
T13599 Benzofurodil CB4091,Benfurodil,Eudilat Others
Benzofurodil is cardiotonic used for the chronic treatment of congestive heart failure.
T39063 Azilsartan mepixetil
Azilsartan mepixetil is a potent angiotensin II receptor antagonist with enhanced efficacy and prolonged duration of action. It exhibits more prominent and sustained effects in lowering blood pressure and heart rate, whi...
T61407 TRPC3/6-IN-1
TRPC3/6-IN-1 is a highly potent and selective inhibitor that specifically blocks the activity of the canonical transient receptor channels TRPC3 and TRPC6. It exhibits a significant blocking potency against the human iso...
T78657 Azilsartan mepixetil potassium QR-01019K
Azilsartan medoxomil potassium (QR-01019K), an angiotensin II receptor antagonist, exhibits a potent and sustained antihypertensive effect, along with a more pronounced and enduring reduction in heart rate, and a high sa...
T21485 Perindopril
Perindopril (S-9490) is a long-acting ACE inhibitor effective for 24 hours, primarily utilized in the management of high blood pressure, heart failure, or stable coronary artery disease. Available as perindopril arginine...
T62005 Imidapril
Imidapril (TA-6366 free base) is an orally active inhibitor of angiotensin-converting enzyme (ACE) and MMP-9. Imidapril inhibits the conversion of angiotensin I to angiotensin II, thereby reduces total peripheral resista...
T72213 Efonidipine hydrochloride NZ-105 hydrochloride
Efonidipine HCl (NZ-105) serves as both a T-type and L-type calcium channel blocker. This compound, distinct from other calcium channel blockers, notably increases N(6), 2'-O-dibutyryladenosine 3',5'-cyclic monophosphate...
TargetMol